Between 1821 and 1880, the Santa Fe Trail was primarily a commercial highway connecting Missouri and Santa Fe, New Mexico. From 1821 until 1846, it was an international commercial highway used by Mexican and American traders. In 1846, the Mexican-American War began. The Army of the West followed the Santa Fe Trail to invade New Mexico. When the Treaty of Guadalupe ended the war in 1848, the Santa Fe Trail became a national road connecting the United States to the new southwest territories. Commercial freighting along the trail continued, including considerable military freight hauling to supply the southwestern forts. The trail was also used by stagecoach lines, thousands of gold seekers heading to the California and Colorado gold fields, adventurers, fur trappers, and emigrants. In 1880 the railroad reached Santa Fe and the trail faded into history.

As the harbinger of America's westward expansion, the Oregon Trail was the pathway to the Pacific for fur traders, gold seekers, missionaries and others. Beginning in 1841 and continuing for more than 20 years, an estimated 300,000 emigrants followed this route from Independence, Missouri to Oregon City, Oregon on a trip that took five months to complete. The 2,170 mile long trail passes through Missouri, Kansas, Nebraska, Wyoming, Idaho and Oregon.

The California Trail carried over 250,000 gold-seekers and farmers to the gold fields and rich farmlands of California during the 1840's and 1850's, the greatest mass migration in American history. Today, more than 1,000 miles of trail ruts and traces can still be seen in the vast undeveloped lands between Casper Wyoming and the West Coast, reminders of the sacrifices, struggles, and triumphs of early American travelers and settlers. More than 240 historic sites along the trail will eventually be available for public use and interpretation. The trail passes through the states of Missouri, Kansas, Nebraska, Colorado, Wyoming, Idaho, Utah, Nevada, Oregon, and California.

Jefferson National Expansion Memorial consists of the Gateway Arch, the Museum of Westward Expansion, and St. Louis' Old Courthouse. During a nationwide competition in 1947-48, architect Eero Saarinen's inspired design for a 630 foot stainless steel arch was chosen as a perfect monument to the spirit of the western pioneers. The Museum of Westward Expansion, located below the Arch, is as large as a football field and contains an extensive collection of artifacts, mounted animal specimens, an authentic American Indian tipi, and an overview of the Lewis and Clark expedition. Located just two blocks west of the Arch, the Old Courthouse is one of the oldest standing buildings in St. Louis, begun in 1839. It was here that the first two trials of the Dred Scott case were held in 1847 and 1850. Today, the building houses a museum charting the history of the city of St. Louis and restored courtrooms.

In 1804, Meriwether Lewis & William Clark began a voyage of discovery with 45 men, a keelboat, two pirogues,and a dog. They departed from Camp Wood located in what was to become Illinois. They traveled over a three-year period through lands that later became 11 states. Most of the trail follows the Missouri & Columbia Rivers. Much has changed in 200 years but trail portions remain intact. At 3700 miles, Lewis & Clark NHT is the second longest of the 23 National Scenic & National Historic Trails. It begins at Hartford, IL & passes through portions of MO, KS, IA, NE, SD, ND, MT, ID, OR, & WA. Many people follow the trail by auto; others find adventure in the sections that encourage boating, biking, or hiking. You can still see the White Cliffs in Montana as Lewis & Clark did. You may stand where they stood looking over the rolling plains at Spirit Mound in South Dakota. You might meet the descendants of the people who hosted Lewis & Clark all along the trail. It remains for your discovery.

The Pony Express National Historic Trail was used by young men on fast paced horses to carry the nation's mail across the country, from St. Joseph, Missouri to Sacramento, California, in the unprecedented time of only ten days. Organized by private entrepreneurs, the horse-and-rider relay system became the nation's most direct and practical means of east-west communications before the telegraph. Though only in operation for 18 months, between April 1860 and October 1861, the trail proved the feasibility of a central overland transportation route, and played a vital role in aligning California with the Union in the years just before the Civil War. Most of the original trail has been obliterated either by time or human activities. Along many segments, the trail's actual route and exact length are matters of conjecture. However, approximately 120 historic sites may eventually be available to the public, including 50 existing Pony Express stations or station ruins.